Learn More
The study of six families with dominant optic atrophy (DOA) originating from the neighbourhood of Leiden revealed that four could be connected through a common ancestor. A detailed analysis of 89 patients permitted a subdivision of the three remaining families into two groups: one with on the average a low visual acuity (less than 0.1) and the other with a(More)
BACKGROUND Whole genome amplification is an increasingly common technique through which minute amounts of DNA can be multiplied to generate quantities suitable for genetic testing and analysis. Questions of amplification-induced error and template bias generated by these methods have previously been addressed through either small scale (SNPs) or large scale(More)
In bacterial photosynthetic reaction centers, ultrafast singlet excited state energy transfer occurs from the monomeric bacteriochlorophylls, B, and bacteriopheophytins, H, to the homodimer special pair, a pair of strongly interacting bacteriochlorophylls. In the M202HL mutant, one of the bacteriochlorophylls comprising the special pair is replaced by a(More)
In bacterial photosynthetic reaction centers, ultrafast singlet excited-state energy transfer occurs from the mono-meric bacteriochlorophylls, B, and bacteriopheophytins, H, to the homodimer special pair, P, a pair of strongly interacting bacteriochlorophylls. Using fluorescence upconversion spectroscopy, energy transfer to the special pair can be monitored(More)
The triplet state of aromatic molecules forms and decays by intersystem crossing, as originally demonstrated by Kasha and Lewis. By contrast, the triplet state of the primary electron donor, 3 P, in photosynthetic reaction centers is formed exclusively by spin-and magnetic-field-dependent charge recombination of the initially formed radical ion pair. 3 P(More)
  • 1