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1999
2018
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Journals and Conferences
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- Alex Straiker, Ken Mackie
- The Journal of physiology
- 2005
Depolarization-induced suppression of excitation and inhibition (DSE and DSI) appear to be important forms of short-term retrograde neuronal plasticity involving endocannabinoids (eCB) and the… (More)
- Brady K. Atwood, Jacqueline Ann Lopez, James B Wager-Miller, Ken Mackie, Alex Straiker
- BMC Genomics
- 2010
G protein coupled receptors (GPCRs) are one of the most widely studied gene superfamilies. Thousands of GPCR research studies have utilized heterologous expression systems such as human embryonic… (More)
- Alex Straiker, Gerald H. Maguire, Ken Mackie, Jason Lindsey
- Investigative ophthalmology & visual science
- 1999
PURPOSE
To determine the presence and distribution of CB1 cannabinoid receptors within the human eye.
METHODS
A subtype-specific affinity-purified polyclonal antibody to the cannabinoid CB1… (More)
- Alex Straiker, Nephi Stella, Daniele Piomelli, Ken Mackie, Harvey J. Karten, Gerald H. Maguire
- Proceedings of the National Academy of Sciences…
- 1999
CB1, a cannabinoid receptor enriched in neuronal tissue, was found in high concentration in retinas of rhesus monkey, mouse, rat, chick, goldfish, and tiger salamander by using a subtype-specific… (More)
- Alex Straiker, Sherry Shu-Jung Hu, +4 authors Ken Mackie
- Molecular pharmacology
- 2009
Depolarization-induced suppression of excitation (DSE) is a major form of cannabinoid-mediated short-term retrograde neuronal plasticity and is found in numerous brain regions. Autaptically cultured… (More)
- Brady K. Atwood, James B Wager-Miller, Christopher W Haskins, Alex Straiker, Ken Mackie
- Molecular pharmacology
- 2012
Receptor internalization increases the flexibility and scope of G protein-coupled receptor (GPCR) signaling. CB(1) and CB(2) cannabinoid receptors undergo internalization after sustained exposure to… (More)
- Alex Straiker, Jane M. Sullivan
- Journal of neurophysiology
- 2003
Cannabinoid CB1 receptors have been detected in retinas of numerous species, with prominent labeling in photoreceptor terminals of the chick and monkey. CB1 labeling is well-conserved across species,… (More)
- Sherry Shu-Jung Hu, Andy Arnold, +5 authors Alex Straiker
- The Journal of comparative neurology
- 2010
Cannabinoid receptors and their ligands constitute an endogenous signaling system that is found throughout the body, including the eye. This system can be activated by Delta(9)-tetrahydrocannabinol,… (More)
- Anke Witting, Lanfen Chen, +6 authors Nephi Stella
- Proceedings of the National Academy of Sciences…
- 2006
Focal cerebral ischemia and traumatic brain injury induce an escalating amount of cell death because of harmful mediators diffusing from the original lesion site. Evidence suggests that healthy cells… (More)
- Alex Straiker, Qing Lu, Gerald H. Maguire
- Visual neuroscience
- 2000
To date, two cannabinoid receptors, CB1 and CB2, have been cloned. The CB1 receptor has been found in a variety of tissues, particularly in the brain. CB2 receptor mRNA is mainly expressed in the… (More)