Alex Schumacher

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During in-vitro culture rabbit early cleavage stages (Day 1 p.c.) and compacted morulae (Day 3 p.c.) were exposed to visible light or to room temperature (23 degrees C) for various lengths of time (0.5-24 h). The light source used resembled closely routine laboratory lighting. Controls were cultured simultaneously for 24 h under standard conditions (37(More)
Possible adverse effects of in vitro culture-associated physical factors were studied in 3- and 4-day-old rabbit embryos. Laboratory conditions were mimicked by exposure to visible light (320-740 nm, 1600 lx) or decreased temperature (22 +/- 1 degree C). Embryos were exposed for a 24-hr period followed by either immediate evaluation or an additional 24 hr(More)
Adverse effects of simultaneous exposure to visible light and room temperature were investigated in rabbit early cleavage stages and morulae. Routine laboratory conditions were mimicked as close as possible. Embryonic development was assessed by cell proliferation via incorporation of tritiated thymidine, by gross morphology, and by electron microscopy.(More)
The correlation between strain fecundity and (i) development and (ii) rate of aneuploidy was studied in rabbit preimplantation embryos obtained from 2 strains of different fecundity. Embryos were investigated at Days 3-6 (preimplantation development) or Days 2, 4 and 6 post coitum (aneuploidy). Embryonic size and cell proliferation varied on the days of(More)
DNA ploidy and S-phase fractions were assessed by flow cytometry in colonic biopsy specimens from 28 patients with ulcerative colitis and 51 with Crohn's disease. Whereas only diploid DNA histograms were found in Crohn's disease and control subjects, three patients with ulcerative colitis exhibited DNA aneuploidy. In one case, aneuploidy was associated with(More)
The transferrin type of 238 Dama serums was determined and an estimate made of the gene frequencies. Using the SANGHVI method, the distribution of the transferrin types of the Dama was compared with 53 African populations south of the Sahara. The comparison demonstrates the great dissimilarity of the Dama to the Khoisanide tribes and confirms--at least in(More)