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BACKGROUND Lassa fever (LF), an often-fatal hemorrhagic disease caused by Lassa virus (LASV), is a major public health threat in West Africa. When the violent civil conflict in Sierra Leone (1991 to… (More)
BACKGROUND Sore throat or pharyngitis is an extremely prevalent condition in primary care. There is a diagnostic dilemma in differentiating bacterial and non-bacterial infections for adequate use of… (More)
BackgroundSera from convalescent Lassa fever patients often contains antibodies to Lassa virus (LASV) glycoprotein 1 (GP1), and glycoprotein 2 (GP2); Immunization of non-human primates with viral… (More)
BackgroundThere is a significant requirement for the development and acquisition of reagents that will facilitate effective diagnosis, treatment, and prevention of Lassa fever. In this regard,… (More)
Abstract Many thermophilic enzymes exhibit increased thermal stability at high pressures. Improved stability under pressure appears to be closely related to enzyme thermostability; however, the… (More)