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  • Alex Kentsis, Ivan Topisirovic, Biljana Culjkovic, Ling Shao, Katherine L. B. Borden
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2004 (First Publication: 28 December 2004)
  • The eukaryotic translation initiation factor eIF4E is deregulated in many human cancers, and its overexpression in cells leads to malignant transformation. Oncogenic properties of eIF4E are directlyContinue Reading
  • Alex Kentsis, Erica Christine Dwyer, +4 authors Katherine L. B. Borden
  • Biology, Medicine
  • Journal of molecular biology
  • 2001 (First Publication: 1 September 2001)
  • The promyelocytic leukemia protein (PML) is a mammalian regulator of cell growth which is characteristically disrupted in acute promyelocytic leukemia and by a variety of viruses. PML contains a RINGContinue Reading
  • Christina M. Ulane, Alex Kentsis, Cristian D. Cruz, Jean-Patrick Parisien, Kristi L. Schneider, Curt M Horvath
  • Biology, Medicine
  • Journal of virology
  • 2005 (First Publication: 15 August 2005)
  • Transcription regulators STAT1 and STAT2 are key components of the interferon signaling system leading to innate antiviral immunity. The related STAT3 protein is a regulator of interleukin-6-typeContinue Reading
  • George S. Laszlo, Todd A. Alonzo, +10 authors Roland B. Walter
  • Medicine
  • Journal of Hematology & Oncology
  • 2015 (First Publication: 20 October 2015)
  • BackgroundRecent studies have identified myocyte enhancer factor 2C (MEF2C) as cooperating oncogene in acute myeloid leukemia (AML) and suggested a contribution to the aggressive nature of at leastContinue Reading
  • Sebastian T. Berger, Saima Ahmed, +5 authors Hanno Steen
  • Biology, Medicine
  • Molecular & cellular proteomics : MCP
  • 2015 (First Publication: 1 October 2015)
  • We describe a 96-well plate compatible membrane-based proteomic sample processing method, which enables the complete processing of 96 samples (or multiples thereof) within a single workday. ThisContinue Reading