Alex Hatton

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BACKGROUND Hypothetically, psychotic disorders could be caused or conditioned by immunological mechanisms. If so, one might expect there to be peripheral immune system phenotypes that are measurable in blood cells as biomarkers of psychotic states. METHODS We used multi-parameter flow cytometry of venous blood to quantify and determine the activation(More)
In order to develop protein formulations that limit aggregation, researchers heuristi-cally screen potential solution additives (excipients). Such screening is necessary because current understanding of mechanisms of aggregation and molecular-level effects of additives on aggregation is limited. In this study, we developed a statistical-mechanical method in(More)
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