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Inflammation is the process by which an organism responds to tissue injury involving both immune cell recruitment and mediator release. Diverse causes of neuropathic pain are associated with excessive inflammation in both the peripheral and central nervous system which may contribute to the initiation and maintenance of persistent pain. Chemical mediators,(More)
OBJECTIVE To determine the extent and severity of illness and mode of transmission of Chlamydia pneumoniae infection in 3 nursing home outbreaks. DESIGN AND SETTING Retrospective cohort study in 3 nursing homes in Ontario from September to November 1994. SUBJECTS A total of 549 residents and 65 staff members. MAIN OUTCOME MEASURES Morbidity and(More)
Comparisons were made between Vero cell assay (VCA) and PCR as indicators for the detection of verocytotoxigenic Escherichia coli (VTEC; also known as Shiga-like toxin-producing E. coli) and as predictors of VTEC isolation from bovine and human fecal samples. Fecal samples were collected as part of a survey on the prevalence of VTEC on dairy farms in(More)
Assurance cases are gaining momentum across several industries as a way to assure critical properties of engineered systems. In the space industry, they promise to help assure spacecraft safing, a fallback mode commonly included in spacecraft to respond to critical faults and keep the vehicle safe until ground operators can resolve the problem. We(More)
Risk factors for prevalent infection with verocytotoxigenic Escherichia coli (VTEC) were studied in a random sample of 886 cows and 592 calves under 3 months of age on 80 randomly selected dairy farms in southern Ontario. Fecal-culture supernatants from each animal were screened for verocytotoxicity using a Vero cell assay (VCA) and for verocytotoxin (VT)(More)
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