Alex Freire Sandes

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OBJECTIVE To evaluate the outcomes of acute myeloid leukemia patients who were older than 60 years of age at the time of diagnosis following the implementation of a treatment algorithm based on age, performance status, and cytogenetic results. METHODS We retrospectively compared the results of 31 elderly acute myeloid leukemia patients (median age of 74(More)
INTRODUCTION Myelodysplastic syndromes (MDS) are clonal disorders characterized by bone marrow (BM) failure and an increased risk of transformation into acute myeloid leukemia (AML). Typically, MDS patients are elderly and are already anemic, leucopenic and/or thrombocytopenic upon presentation. Despite their myeloid origin, many MDS cases show(More)
A 78-year-old woman hospitalized for investigation of ascites presented with weakness, loss of appetite, fever, and chills. 9 /L) and distorted granulocytes containing toxic vacuoles and intracellular structures that exhibit a uniform and definite rod shape (arrows), suggestive of phagocytized bacilli (panels A-B). Blood cultures confirmed the blood smear(More)
Platelet satellitism is an in vitro phenomenon involving platelet rosetting around mature granulocytes that is observed exclusively in edetic acid (EDTA)-treated peripheral blood at room temperature (1). The precise underlying mechanism of platelet satellitism remains to be fully elucidated but the current explanations include an immunologic mechanism,(More)
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