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BACKGROUND The prevalence of obesity has increased at an alarming rate worldwide. Some studies have observed an association between iron (Fe) deficiency (ID) and obesity, however more research is needed. OBJECTIVE To assess whether body mass index (BMI) is associated with both Fe absorption and Fe status. METHODS A cross sectional sample of 318 Chilean(More)
UNLABELLED Background: The current magnitude of folate and vitamin B12 deficiency in Latin America and the Caribbean is uncertain. OBJECTIVE To summarize data on plasma or serum vitamin B12 and folate concentrations in Latin America and the Caribbean reported since 1990, a period that covers the era before and after the introduction of folic acid(More)
The aim of the present study was to assess the effect of severe head injury over resting energy expenditure and nitrogen losses. Eight patients with severe head trauma (mean Glasgow scale of 4.9 +/- 1.6), subjected to emergency craniotomy were studied; four patients had septic complications and none received steroids. Energy expenditure was measured using(More)
OBJECTIVE To determine the prevalence of anemia and iron status among Chilean women of childbearing age between 1981 and 2010. MATERIALS AND METHODS Calculation of the prevalence of anemia and iron status was based on multiple cross-sectional iron absorption studies performed in 888 women during this period of time. All studies included measurements of(More)
OBJECTIVE The aim of this study was to determine the effect of combined calcium and iron versus single iron supplementation on iron status in Bolivian schoolchildren. METHODS Children ages 6 to 10 y old (N = 195), were randomly assigned to receive either 700 mg Ca (as calcium carbonate) plus 30 mg Fe (as ferrous sulfate) (Ca + Fe group) or 30 mg Fe (as(More)
BACKGROUND A novel approach to determine vitamin B12 status is to combine four blood markers: total B12 (B12), holotranscobalamin (holoTC), methylmalonic acid (MMA) and total homocysteine (tHcy). This combined indicator of B12 status is expressed as cB12=log10[(holoTC·B12)/(MMA·Hcy)]-(age factor). Here we calculate cB12 in datasets with missing biomarkers,(More)
BACKGROUND The prevalence of vitamin D deficiency in Latin America and the Caribbean is unknown. OBJECTIVE To examine the prevalence data available on vitamin D deficiency in Latin America and the Caribbean. METHODS A systematic review was conducted in 2011. Studies using biochemical biomarkers and dietary intake estimation were included. Studies(More)
BACKGROUND Iron deficiency is the most prevalent nutritional deficiency in the world, primarily affecting infants, young children, and women of childbearing age. OBJECTIVE To evaluate the impact of the National Complementary Feeding Program (NCFP) on anemia and iron status in Chilean children aged 11 to 18 months. METHODS Two studies were performed. The(More)
During the past decade the role of folate and vitamin B12 in human nutrition have been under constant re-examination. Basic knowledge on the metabolism and interactions between these essential nutrients has expanded and multiple complexities have been unraveled. These micronutrients have shared functions and intertwined metabolic pathways that define the(More)
BACKGROUND In 1974/75, the prevalence of anemia in Chilean preschoolers was 18.8%. Since 2000, the Chilean Ministry of Health has combated anemia through the delivery of iron-fortified milk by the National Complementary Feeding Program (NCFP). OBJECTIVE To determine the prevalence of anemia in children aged 19 to 72 months who are beneficiaries of the(More)