Alex Brandts

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The median of k≥3 genomes was originally defined to find a compromise genome indicative of a common ancestor. However, in gene order comparisons, the usual definitions based on minimizing the sum of distances to the input genomes lead to degenerate medians reflecting only one of the input genomes. “Near-medians”, consisting of equal samples of gene(More)
The morphogenetic mechanisms in the development of polyps were deducted from the structure of the mucous membrane and the distribution of the epithelial proliferation activity in various layers of the mucosa. Demonstration of the structure of the mucosa was effected by graphical-perspective partial reconstruction; the parameter used of proliferation(More)
To understand the particular evolutionary patterns of plant genomes, there is a need to systematically survey the fate of the subgenomes of polyploids fixed as whole genome duplicates, including patterns of retention of duplicate, triplicate, etc. genes. We measure the simultaneous dynamics of duplicate orthologous gene loss in rosids, in asterids, and in(More)
1. The effects of diadenosine polyphosphates (APnA, where n = 4-6) were studied on beating frequency of perfused guinea-pig hearts and on muscarinic K+ current (IK(ACh)) and ATP-regulated K+ current (IK(ATP)) in atrial myocytes from guinea-pig hearts using whole-cell voltage clamp. 2. Bradycardia induced by APnA in perfused hearts was completely inhibited(More)
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