Alessandro Salvi

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CDK5R1 encodes p35, a specific activator of the serine/threonine kinase CDK5, which plays crucial roles in CNS development and maintenance. CDK5 activity strongly depends on p35 levels and p35/CDK5 misregulation is deleterious for correct CNS function, suggesting that a tightly controlled regulation of CDK5R1 expression is needed for proper CDK5 activity.(More)
Smart cities and smart mobility represent two of the most significative real use case scenarios in which there is an increasing demand for collecting, elaborating, and storing large amounts of heteroge-nous data. In urban and mobility scenarios issues like data trustiness and data and network security are of paramount importance when considering smart(More)
Hepatocellular carcinoma (HCC) is a challenging malignancy of global importance, it is the third most common cause of cancer-related mortality worldwide. In the last years the multikinase inhibitor sorafenib has been used for advanced HCC, but some patients do not benefit from this therapy; thus, novel therapeutic options based on molecular approaches are(More)
In human hepatocellular carcinoma (HCC), the high expression of urokinase-type plasminogen activator (uPA) is an unfavorable prognostic factor and a therapeutic target. To identify the downstream effects of uPA silencing by RNA interference, we studied proteome modifications of uPA-inhibited SKHep1C3 cells, an HCC-derived cell line. The study with(More)
— In this paper the Cooperative Adaptive Cruise Control strategy for vehicles platooning is extended to the case when each vehicle can communicate with a subset of vehicles in the fleet. The control objective is to guarantee that the fleet moves forward with a given spacing policy at the leader velocity. To this aim each vehicle decides its control action(More)
—Automated and coordinated vehicles' driving (pla-tooning) is gaining more and more attention today and it represents a challenging scenario heavily relying on wireless Inter-Vehicular Communication (IVC). In this paper, we propose a novel controller for vehicle platooning based on consensus. Opposed to current approaches where the logical control topology(More)