Alessandro Davoli

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OBJECTIVE Amyotrophic lateral sclerosis (ALS) is a motor neuron disease whose pathophysiological deficits, causing impairment in motor function, are largely unknown. Here we propose that hydrogen sulfide (H2 S), as a glial-released inflammatory factor, contributes to ALS-mediated motor neuron death. METHODS H2 S concentrations were analyzed in the(More)
Trace amines (TAs) are a class of endogenous compounds strictly related to classic monoamine neurotransmitters with regard to their structure, metabolism, and tissue distribution. Although the presence of TAs in mammalian brain has been recognized for decades, until recently they were considered to be by-products of amino acid metabolism or as "false"(More)
Molecular Neurobiology Unit, IRCCS-Fondazione Santa Lucia, 00143 Rome, Italy Neurophysiopathology Unit, Department of System Medicine, University of Rome “Tor Vergata”, 00133 Rome, Italy Department of Experimental Medicine and Surgery, University of Rome “Tor Vergata”, 00133 Rome, Italy Proteomics and Metabonomics Unit, IRCCS-Fondazione Santa Lucia, 00143(More)
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