Aleksandr Kravchenko

  • Citations Per Year
Learn More
Azobenzene-containing polymers (azopolymers) have attracted great interest due to their potential use in various technological applications, including holographic recording, photomechanics, diffractive optics, and microand nanopatterning. [ 1–7 ] These applications are brought about by the effi cient and reversible photoisomerization of the azobenzene(More)
The methods of the quality control of medical biological preparations, including tests on animals, do not ensure the complete absence of toxicity in a final product. The use of the method of "subcultures with the introduced preparation" makes it possible to determine the toxicity of both specific and nonspecific components of vaccines and sera from the(More)
Different batches of the same preparation manufactured at the same enterprise, or at different enterprises, in accordance with the same manufacturing regulations have been found to be capable of producing a damaging effect of different intensity on the continuous cell culture L132. The titers vary, according to their cytotoxic effect, from 1 : 32 to 1(More)
Besides specific antigens medical immunobiological agents (MIBA) contain chemical compounds (formaldehyde, aluminium hydroxide and mercury salt, merthiolate) in permissible concentrations. Therefore, the investigation of MIBA and their components should involve methods studying the effect of chemical compounds on cells and their structural components. For(More)
It is in the reinoculated cell line FL that the sensitivity of cells under the action of a small dose of diphtheria toxin (DT) changes to the toxin itself as well as to the Coxsackie enterovirus. (B-5). After surviving the infection and getting again "healthy", the cells have acquired simultaneously an elevated sensibility to DT and reduced susceptibility(More)
Administration to guinea pigs of 1/Dlm of diphtheria exotoxin twice at an interval of 1 and 24 hours, or once in a dose of 25/100 Dlm caused changes in the activity of the redox enzymes. The character of their changes in the animals to which the whole dose of the exotoxin was administered once or repeatedly was directly reverse: in the first case the(More)