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Smoothened agonist augments proliferation and survival of neural cells
- O. Bragina, S. Sergejeva, +4 authors Aleksandr Žarkovsky
- Biology, Medicine
- Neuroscience Letters
- 27 September 2010
In vitro experiments demonstrated that SAG in low-nanomolar concentrations induces proliferation of neuronal and glial precursors without affecting the differentiation pattern of newly produced cells and, in contrast to Shh, SAG did not induce neurotoxicity in neuronal cultures. Expand