Alejandro Millán

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Glutamate, the major excitatory neurotransmitter, induces a wide array of signals from the membrane to the nucleus regulating gene expression. In Bergmann glia, Ca2+ -permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole- propionic acid (AMPA) receptors are involved in the short- and long-term interactions between these cells and the neurons that they(More)
Glial glutamate receptors are likely to play a role in plasticity, learning, and memory and in a number of neuropathologies. An enhanced glutamate-dependent tyrosine phosphorylation has been detected in such processes. Using primary cultures of chick Bergmann glia cells and chick cerebellar slices, we addressed whether glial glutamate receptors can activate(More)
In this work, we present a computational behavioralmodel for logic gates called Internode (Internal Node LogicComputational Model) that considers the functionality ofthe gate as well as all the different internal states the gatecan reach. This computational model can be used in logic-leveltools and is valid for any dynamic behavioral model(delay models,(More)
Epidemiological studies and animal models suggest a link between high levels of dietary fat intake and an increased risk of developing breast cancer. Particularly, free fatty acids (FFAs) are involved in several processes, including proliferation, migration and invasion, in breast cancer cells. Linoleic acid (LA) is a dietary n-6 polyunsaturated fatty acid(More)
This contribution successfully accomplished the design and implementation of an advanced DSP circuit for direct measurements of electrical network parameters (RMS and real and reactive power) with application to network monitoring and quality assurance. The device is implemented on a mid-range Xilinx Spartan-3 family FPGA and includes an OPE interface so(More)
In this paper, we present a model, Internode, that unifies the gate functional behavior and the dynamic one. It is based on a FSM that represents the internal state of the gate depending on the electrical load of its internal nodes allowing to consider aspects like input collisions and internal power consumption. Also, we explain the importance of internal(More)