Alejandro Lorente

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A new generation of biologics targeting the interleukin-23-T helper 17 pathway has been developed. This study aimed to assess the short-term effectiveness and safety of these new agents using a network meta-analysis. Twenty-seven randomized clinical trials (10 629 patients) were identified by a comprehensive systematic literature review (PROSPERO 2015:(More)
STUDY DESIGN A prospective evaluation of cardiorespiratory function following spinal fusion in adolescent idiopathic scoliosis (AIS). OBJECTIVES To evaluate the cardiopulmonary function during exercise in patients with severe AIS, before and two years after undergoing a posterior spinal fusion. SUMMARY OF BACKGROUND DATA After surgical correction of(More)