Alejandro González

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We develop and present a portable tool intended for real time estimation of the center of mass (CoM) in human subjects. Using the statically equivalent serial chain (SESC) method we can account for subject specificity after identification of the model’s parameters. CoM position estimates are then available from measurements of the subject's limbs(More)
The trajectory of the whole body center of mass (CoM) is useful as a reliable metric of postural stability. If the evaluation of a subject-specific CoM were available outside of the laboratory environment, it would improve the assessment of the effects of physical rehabilitation. This paper develops a method that enables tracking CoM position using low-cost(More)
  • María E Sáez, María T Martínez-Larrad, Reposo Ramírez-Lorca, José L González-Sánchez, Carina Zabena, María J Martinez-Calatrava +4 others
  • 2007
BACKGROUND Genes implicated in common complex disorders such as obesity, type 2 diabetes mellitus (T2DM) or cardiovascular diseases are not disease specific, since clinically related disorders also share genetic components. Cysteine protease Calpain 10 (CAPN10) has been associated with T2DM, hypertension, hypercholesterolemia, increased body mass index(More)
TRPM8, a nonselective cation channel activated by cold, voltage, and cooling compounds such as menthol, is the principal molecular detector of cold temperatures in primary sensory neurons of the somatosensory system. The N-terminal domain of TRPM8 consists of 693 amino acids, but little is known about its contribution to channel function. Here, we(More)
Glucagon hormone is synthesized and released by pancreatic α-cells, one of the islet-cell types. This hormone, along with insulin, maintains blood glucose levels within the physiological range. Glucose stimulates glucagon release at low concentrations (hypoglycemia). However, the mechanisms involved in this secretion are still not completely clear. Here,(More)
  • María E. Sáez, José L. González-Sánchez, Reposo Ramírez-Lorca, María T. Martínez-Larrad, Carina Zabena, Alejandro González +3 others
  • 2008
Cardiovascular disease is the leading cause of morbidity and mortality in the industrialized world. Familial aggregation of cardiovascular risk factors is a frequent finding, but genetic factors affecting its presentation are still poorly understood. The calpain 10 gene (CAPN10) has been associated with type 2 diabetes (T2DM), a complex metabolic disorder(More)
Pedestrian classifiers decide which image windows contain a pedestrian. In practice, such classifiers provide a relatively high response at neighbor windows overlapping a pedestrian, while the responses around potential false posi-tives are expected to be lower. An analogous reasoning applies for image sequences. If there is a pedestrian located within a(More)
This study investigates the possibility of using the so-called Statically Equivalent Serial Chain approach to estimate the subject-specific 3D whole-body centre of mass (CoM) location. This approach is based on a compact formulation of the 3D whole-body CoM position associated with a least squares identification process. This process requires a calibration(More)
The concept of a quantum heat engine (QHEN) has been discussed in the literature, not only due to its intrinsic scientific interest, but also as an alternative to efficiently recover, on a nanoscale device, thermal energy in the form of useful work. The quantum character of a QHEN relies, for instance, on the fact that any of its intermediate states is(More)