Alejandro González Álvarez

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OBJECTIVE To quantify levels of exposure to cytotoxic drugs among health professionals in order to establish an exposure threshold and implement measures to increase protection and safety. MATERIAL AND METHOD Contamination with 5-fluorouracil, gemcitabine and cyclophosphamide was measured on work surfaces in the following areas: a class II type B3(More)
PURPOSE To assess the economic impact derived from the widening of the administration intervals of adalimumab (ADA) and etanercept (ETN) for the treatment of rheumatoid arthritis (RA) and spondyloarthropathies (SAP) at our working environment. MATERIAL AND METHODS A budget impact model (BIM) was developed to estimate the economic impact that would have(More)
INTRODUCTION Global developmental delay (GDD) and intellectual disability (ID) are frequent reasons for consultation in paediatric neurology departments. Nowadays, array comparative genomic hybridisation (array-CGH) is one of the most widely used techniques for diagnosing these disorders. Our purpose was to determine the phenotypic features associated with(More)
El retraso global del desarrollo (RGD) y la discapacidad intelectual (DI) constituyen una enfermedad muy frecuente, con notable impacto social y etiología variada. El estudio de los cromosomas mediante array-CGH ha incrementado, en más de un 20%, el número de diagnósticos etiológicos en nuestra consulta de neuropediatría1. Presentamos los casos clínicos de(More)
PURPOSE To assess the effectiveness and efficiency of the two alternatives mainly used in our area, etanercept (ETN) and adalimumab (ADA), for the treatment of rheumatoid arthritis (RA) patients under real clinical practice. MATERIAL AND METHODS We performed a retrospective observational study, where the time horizon was 12 months referred to the year(More)
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