BACKGROUND AND PURPOSE The α3β4 subtype of nicotinic acetylcholine receptors (nAChRs) has been implicated in mediating nicotine reinforcement processes. AT-1001 has been recently described as a high-affinity and selective α3β4 nAChR antagonist that blocks nicotine self-administration in rats. The aim of this study was to investigate the mechanism of action… (More)
In this paper we present a model designed on the basis of the neurophysiology of the rat hippocampus to control the navigation of a real robot. The model allows the robot to learn reward locations dynamically moved in different environments, to build a topological map, and to return home autonomously. We describe robot experimentation results from our tests… (More)
Extracellular and intracellular copper and zinc regulate synaptic activity and plasticity, which may impact brain functionality and human behavior. We have found that a metal coordinating molecule, Neocuproine, transiently increases free intracellular copper and zinc levels (i.e., min) in hippocampal neurons as monitored by Phen Green and FluoZin-3… (More)
Adherence Inhibition of Human Pathogens Campylobacter jejuni and Campylobacter coli by Non-digestible Oligosaccharides" (2014).