Aleida Maria da Silva Lima

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Water-insoluble glucan was isolated from the baker's yeast Saccharomyces cerevisiae. The yeast cells were treated with alkali and the residue then with acid. Chemical and NMR (1D and 2D) analyses showed that a linear (1→3)-β-glucan was purified that was not contaminated with other carbohydrates, proteins or phenolic compounds. The effects of the glucan on(More)
Human papillomavirus (HPV) is the main etiological factor for cervical cancer development. HPV is also associated with other anogenital and oropharyngeal tumors. HPV associated tumors are frequent and constitute a public health problem, mainly in developing countries. Therapy against such tumors is usually excisional, causing iatrogenic morbidity.(More)
Methods Fifty four Balb/C mice of 7 to 10 weeks old under influence of estrogen were inoculated with 5x10 stationaryphase blastoconidia of C. albicans, intravaginally. The mice were divided in three groups, treated with glucan vaginally (5mg/mL) and intraperitoneally (1mg/mL), and the control group that received saline, intraperitoneally. Vaginal lavage was(More)
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