Aldo Pietro Maggioni

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Lipid-lowering treatment with statins clearly reduces morbidity and mortality of patients with documented CAD [1–3]. However, because these trial protocols excluded patients with chronic heart failure, information on the effect of statins in this clinical condition is incomplete. Since the prevalent etiology of heart failure is CAD, its prevention may(More)
Clinicians may be reluctant to implement evidence-based guideline recommendations because they believe that patients with chronic heart failure (CHF) who are enrolled into clinical trials are not truly representative of those seen in routine practice. Moreover, there may also be perceived safety issues associated with polypharmacy in patients with CHF.(More)
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