Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications.
Current rare-variant, gene-based tests of association often suffer from a lack of statistical power to detect genotype–phenotype associations as a result of a lack of prior knowledge of genetic… (More)
We introduce two new bootstraps for exchangeable random graphs. One, the "empirical graphon", is based purely on resampling, while the other, the "histogram stochastic block model", is a model-based… (More)
The aggregation of functionally associated variants given a priori biological information can aid in the discovery of rare variants associated with complex diseases. Many methods exist that aggregate… (More)
We analyze Personalized PageRank (PPR), a local spectral method for clustering, which extract clusters using locally-biased random walks around a user-specified seed node. In constrast to previous… (More)
To date, gene-based rare variant testing approaches have focused on aggregating information across sets of variants to maximize statistical power in identifying genes showing significant association… (More)