Alberto Silletti

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In a double blind evaluation of 60 digital dermatoscopic images by 4 "junior", 4 "senior" and 4 "expert" dermatologists (dermatoscopy training respectively less than 1 year, between 1 and 5 years, and more than 5 years), a significant inter-operator variability was observed in melanocytic lesion border identification (with a disagreement of the order of 10(More)
BACKGROUND The first step in the analysis of a dermatoscopically imaged melanocytic lesion is segmentation--informally, isolating those points in the image belonging to the lesion from those belonging to the surrounding non-lesional skin. Although typically studied in the context of automated analysis, segmentation is a necessary step even for human(More)
Drosophila melanogaster is a model organism in genetics thanks to the compactness of its genome and its relative simplicity. Recently, certain developmental patterns in Drosophila have been studied by mathematical models, with the aim of gaining deeper and quantitative insight into the morphogenesis of this insect. There is a need for accurate dynamical of(More)
VirtualShave is a novel tool to remove hair from digital dermatoscopic images. First, individual hairs are identified using a top-hat filter followed by morphological postprocessing. Then, they are replaced through PDE-based inpainting with an estimate of the underlying occluded skin. VirtualShave's performance is comparable to that of a human operator(More)
OBJECTIVES To investigate the effect of low doses of the angiotensin converting enzyme inhibitor enalapril on renal haemodynamics and albuminuria in normotensive and hypertensive type 1 (insulin-dependent) diabetic patients with incipient or overt nephropathy. METHODS Twenty-two type 1 (insulin-dependent) diabetic patients with persistent microalbuminuria(More)
In this study we evaluated the acceptability of using the first morning urine albumin concentration (FMAC) and the first morning urine albumin/creatinine (FMA/C) ratio as an indirect estimation of timed albumin excretion in order to screen for microalbuminuria in a large diabetic population. Urinary albumin excretion rate (AER) was determined in samples(More)
OBJECTIVE The present study was undertaken to evaluate, by means of angiography, the anatomic pattern of arterial obstructions in the lower extremities of diabetic patients presenting with critical limb ischaemia. We particularly examined the differences in involvement of the foot arteries between patients with and without diabetes. PATIENTS AND METHODS A(More)
Epithelia are sheets of connected cells that are essential across the animal kingdom. Experimental observations suggest that the dynamical behavior of many single-layered epithelial tissues has strong analogies with that of specific mechanical systems, namely large networks consisting of point masses connected through spring-damper elements and undergoing(More)