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SUMMARY Evidence of the presence of substantial quantities of a glucuronic acid conjugate of /V-hydroxy-4-aminobiphenyl in the urine of dogs given 4-aminobiphenyl was obtained. The conjugate is very acid labile, readily liberating free /V-hydroxy-4-aminobiphenyl at lowered pH and in the presence of /3-glucuronidase. It was responsible for ap proximately 25%(More)
SUMMARY Evidence of the presence of substantial quantities of a glucuronic acid conjugate of /V-hydroxy-4-aminobiphenyl in the urine of dogs given 4-aminobiphenyl was obtained. The conjugate is very acid labile, readily liberating free /V-hydroxy-4-aminobiphenyl at lowered pH and in the presence of /3-glucuronidase. It was responsible for ap proximately 25%(More)
The detection of pulmonary nodules is one of the most studied problems in the field of medical image analysis due to the great difficulty in the early detection of such nodules and their social impact. The traditional approach involves the development of a multistage CAD system capable of informing the radiologist of the presence or absence of nodules. One(More)
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