Alberto Medina

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Objectives: To evaluate procalcitonin (PCT) as a diagnostic marker of bacterial sepsis in critically ill neonates and children and to compare the results of PCT with those of C-reactive protein (CRP) and serum amyloid (SAA). Design and setting: Prospective, observational study in neonatal and pediatric intensive care units. Patients: A total of 116 divided(More)
Identification of predictive factors for non-invasive ventilation (NIV) failure and determination of NIV characteristics. Prospective observational study. Paediatric Intensive Care Unit in a University Hospital. A total of 116 episodes were included. Clinical data collected were respiratory rate (RR), heart rate and FiO2 before NIV began. Same data and(More)
INTRODUCTION Parameters allowing regular evaluation of renal function in a paediatric intensive care unit (PICU) are not optimal. The aim of the present study was to analyse the utility of serum cystatin C and beta2-microglobulin (B2M) in detecting decreased glomerular filtration rate in critically ill children. METHODS This was a prospective,(More)
Identification of catheter-related bloodstream infection (CR-BSI) risk factors and determination of whether intervention related to identified risk factors would reduce CR-BSI rates. Prospective, observational, interventional and interrupted time-series study. Pediatric Intensive Care Unit (PICU) in a university hospital. During a 7-year period, 609 central(More)
To analyse the clinical value of procalcitonin (PCT), C-reactive protein (CRP) and leucocyte count in the diagnosis of paediatric sepsis and in the stratification of patients according to severity. Prospective, observational study. Paediatric intensive care unit (PICU). Ninety-four children. Leucocyte count, PCT and CRP were measured when considered(More)
OBJECTIVE To describe the first pediatric case of fatal lactic acidosis in an antiretroviral-treated child with human immunodeficiency virus (HIV) infection. DESIGN Case report. SETTING Pediatric intensive care unit. PATIENTS A patient with fatal antiretroviral therapy-associated type B lactic acidosis. INTERVENTIONS None. MEASUREMENTS AND MAIN(More)
Identification of early mechanical complications (EMC) of central venous catheterizations (CVC) in pediatric patients and determination of EMC risk factors. Prospective observational study. Pediatric intensive-care unit in a university hospital. Eight-hundred and twenty-five CVC were performed in 546 patients. Age, weight, gender, mechanical ventilation,(More)
BACKGROUND Non-invasive ventilation (NIV) may be useful after extubation in children. Our objective was to determine postextubation NIV characteristics and to identify risk factors of postextubation NIV failure. METHODS A prospective observational study was conducted in an 8-bed pediatric intensive care unit (PICU). Following PICU protocol, NIV was(More)
Staphylococcus aureus subsp. anaerobius, a microaerophilic, catalase-negative bacteria, is the etiological agent of abscess disease, a specific chronic condition of sheep and goats, characterized by the formation of necrotic lesions that are typically located in superficial lymph nodes. In this study, molecular analysis including pulsed-field gel(More)
BACKGROUND Vincristine, an antineoplastic agent, must never be injected intrathecally because of its devastating neurotoxic effects, which are usually fatal. We report a case of fatal myeloencephalopathy secondary to inadvertent intrathecal administration of vincristine. CASE REPORT Intrathecal vincristine was inadvertently injected into a twelve-year-old(More)