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Proteolytic processing of lysyl oxidase–like-2 in the extracellular matrix is required for crosslinking of basement membrane collagen IV

This study demonstrates that LOXL2 is processed extracellularly by serine proteases, generating a 65-kDa form lacking the first two scavenger receptor cysteine-rich domains, and demonstrates that proteolytic processing is an important event that allows LO XL2-mediated crosslinking of basement membrane collagen IV.
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Chitosan nanoparticles loaded with garlic essential oil: A new alternative to tebuconazole as seed dressing agent

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The application of ozonated water rearranges the Vitis vinifera L. leaf and berry transcriptomes eliciting defence and antioxidant responses

The response to ozone was observed to be organ and developmental stage-dependent, with a decrease of the number of DEGs in the fruit from the onset of ripening to later stages, and genes related to cell wall development and secondary metabolites were generally down-regulated after ozone treatment.
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Lysyl Oxidase-like-2 Cross-links Collagen IV of Glomerular Basement Membrane*

It is demonstrated that LOXL2 is a novel component of the molecular machinery that forms cross-linked collagen IV networks, which are essential for glomerular basement membrane stability and molecular ultrafiltration function.
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Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects

A novel mouse mutant is characterized that has a defect in collagen glycosylation, which appears to affect muscle development, and it is hypothesized that the Colgalt1 mutant could serve as a model of a human connective tissue disorder and/or congenital muscular dystrophy or myopathy.
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De Novo Polymerase Activity and Oligomerization of Hepatitis C Virus RNA-Dependent RNA-Polymerases from Genotypes 1 to 5

Results presented in this study reveal the existence of genotypic differences in NS5B de novo activity and oligomerization, and allow us to define two regions, one consisting of residues Glu128, Asp129, and Glu248, and the other consisting of residue of αT helix possibly involved in NS 5B-NS5B interactions.
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A New Glycosyltransferase Enzyme from Family 91, UGT91P3, Is Responsible for the Final Glucosylation Step of Crocins in Saffron (Crocus sativus L.)

Results suggest a role of UGT91P3 in the biosynthesis of highly glucosylated crocins in saffron, and that it represents the last missing gene in crocin biosynthesis.
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Identification and characterization of apocarotenoid modifiers and carotenogenic enzymes for biosynthesis of crocins in Buddleja davidii flowers.

Comparative correlation network analysis is used to study how the synthesis of these valuable apocarotenoids diverges among B. davidii, Gardenia jasminoides, and Crocus sativus, highlighting distinctive differences which could be the basis of the differential accumulation of crocins in the three species.
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Comparative evaluation of carvacrol and eugenol chitosan nanoparticles as eco-friendly preservative agents in cosmetics.

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Fortification and bioaccessibility of saffron apocarotenoids in potato tubers

Carotenoids are C40 isoprenoids with well-established roles in photosynthesis, pollination, photoprotection, and hormone biosynthesis. The enzymatic or ROS-induced cleavage of carotenoids generates a…
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