Alberto Honrubia

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BACKGROUND Invasive fungal infections (IFI) are associated with high mortality in liver transplant recipients. Prevention remains an elusive goal, especially for IFI caused by moulds. PATIENTS AND METHODS From January 1998, patients who fulfilled four or more variables identified as risk factors for IFI received a cumulative dose of 1-1.5 g of lipid(More)
BACKGROUND Invasive aspergillosis (IA) is an important cause of mortality in liver transplant patients. Clinical and microbiological diagnosis is difficult, and it is frequently achieved only after autopsy. Early diagnosis and antifungal therapy could improve the survival of these patients. METHODS A retrospective case-control study of IA in liver(More)
The cases of four liver transplant recipients who developed invasive candidiasis (2 cholangitis, 1 perihepatic abscess, 1 candidemia) due to azole-resistantCandida glabrata are reported. Three patients were receiving azolic compounds (2 itraconazole, 1 fluconazole) when the infection was diagnosed. All four patients received fluconazole as intestinal(More)
BACKGROUND Preemptive therapy required highly predictive tests for CMV disease. CMV antigenemia assay (pp65 Ag) has been commonly used for rapid diagnosis of CMV infection. Amplification methods for early detection of CMV DNA are under analysis. OBJECTIVES To compare two diagnostic methods for CMV infection and disease in this population: quantitative PCR(More)
CASE REPORT An elderly patient was referred to the ophthalmologist for evaluation of photopsia. An ophthalmic examination demonstrated no objective visual alterations. The patient had been receiving digitalis for two months. We suspected digitalis intoxication and the patient was remitted to the Emergency Service. The patient's digoxin blood level was(More)