Alberto Cardona

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BACKGROUND Loss of genomic imprinting (LOI) of the insulin-like growth factor-2 gene (IGF2) is an epigenetic change involving abnormal activation of the normally silent maternally inherited allele. LOI of IGF2 gene is found in tumor tissue, normal adjoining mucosa and peripheral blood lymphocytes (PBL) of some patients with colorectal cancer (CRC),(More)
We propose a simple preconditioning for the equations of motion of constrained mechanical systems in index three form. The scaling transformation is applied to the displacement-velocity-multiplier and to the reduced displacement-multiplier forms. The analysis of the transformed system shows that conditioning and sensitivity to perturbations become(More)
In this paper, we present a new numerical method, the Immersed Element-Free Galerkin Method (IEFGM), for the solution of fluid-structure interaction problems. The technique is a variation of the Immersed Finite Element Method developed by (L. Zhang et al., Journal of Fluids and Structures, 23(6):836-857 (2007)) in which the fluid-solid interaction force is(More)
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