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Studies on the Interaction of Alyteserin 1c Peptide and Its Cationic Analogue with Model Membranes Imitating Mammalian and Bacterial Membranes
TLDR
Molecular dynamics results showed that the carboxy-terminal of the peptide +5 has the ability to insert into the surface of the PC/PG membranes, resulting in the increase of the membrane fluidity. Expand
Dual investigation of lanthanide complexes with cinnamate and phenylacetate ligands: Study of the cytotoxic properties and the catalytic oxidation of styrene
Abstract Eleven lanthanide compounds [Y(cinn)3] (1), [La(cinn)3] (2), [La(4-OMecinn)3]·2H2O (3), [La(4-Clcinn)3]·2H2O (4), [La(4-OMephac)3]·4H2O (5), [La(4-Clphac)3]·3H2O (6), [Ce(cinn)3] (7),Expand
Synthesis, antibacterial activity and DNA interactions of lanthanide(III) complexes of N(4)-substituted thiosemicarbazones
This paper reports the synthesis and detailed characterization of six novel lanthanide complexes of La(III), Eu(III) and Nd(III) with N(4)-substituted thiosemicarbazones derived from theExpand
Synthesis, biological evaluation and model membrane studies on metal complexes containing aromatic N,O-chelate ligands
TLDR
Interestingly, the fluorescent properties of these compounds make them potential candidates to monitor the morphology of bacteria at different compound concentrations, and they exhibit higher biological activity than the free ligands, confirming a synergistic effect. Expand
Description and Preliminary Evaluation of a Program for Improving Chemistry Learning in High School Students
High school students have had some difficulties in understanding chemistry due to traditional ways of teaching this specific science. It is important to improve teaching methods that increase studentExpand
Antibacterial Activity of a Cationic Antimicrobial Peptide against Multidrug-Resistant Gram-Negative Clinical Isolates and Their Potential Molecular Targets
TLDR
The interaction between the peptide and genomic DNA (gDNA) showed a hyperchromic effect, which indicates that ΔM2 can denature bacterial DNA strands via the grooves. Expand
In Vitro Evaluation of the Potential Pharmacological Activity and Molecular Targets of New Benzimidazole-Based Schiff Base Metal Complexes
TLDR
A series of lanthanide complexes, including Schiff base ligands derived from 1H-benzimidazol-2-yl)aniline, salicylaldehyde, and 2,4-dihydroxybenzaldehyde were synthesized and characterized using different spectroscopic methods and exhibited notable effect on model membranes imitating mammalian and bacterial membranes and rolled along DNA strands through groove interactions. Expand
A Study of the Interaction of a New Benzimidazole Schiff Base with Synthetic and Simulated Membrane Models of Bacterial and Mammalian Membranes
TLDR
A new Schiff base (Bz-Im) derivative from 2-(m-aminophenyl)benzimidazole and 2,4-dihydroxybenzaldehyde was synthesized and characterized by spectroscopic and spectrometric techniques, and results showed that, at low compound concentrations, the effects were similar in both membrane models. Expand