Albert Manuel Orozco Camacho

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Normal zinc levels are essential for the development and maintenance of immune functions; Zn deficiency is detrimental to the embryo and offspring of experimental animals, especially concerning immune development. It is known that Zn supplementation improves immune responses. To further explore the relation between Zn administration and the metal in vitro(More)
OBJECTIVE Hereditary hemochromatosis (HH) is a disease caused by mutations in the Hfe gene characterised by systemic iron overload and associated with an increased prevalence of osteoarthritis (OA) but the role of iron overload in the development of OA is still undefined. To further understand the molecular mechanisms involved we have used a murine model of(More)
Chronic dipyridamole therapy produces sustained protection against cardiac ische-mia-reperfusion injury. Am.—Sustained protection against ischemia-reperfusion injury is not available for patients at risk for myocardial infarction who may require emergent reperfusion therapy. Whereas ischemic precondition-ing and adenosinergic agents reduce myocardial(More)
Chronic alcohol-induced changes in cardiac contractility are not due to changes in the cytosolic Ca 2ϩ transient. Am.—Long-standing heavy alcohol consumption acts as a chronic stress on the heart. It is thought that alcohol-induced changes of contractility are due to altered Ca 2ϩ handling, but no measurements of cytosolic Ca 2ϩ ([Ca 2ϩ ] c) after chronic(More)
Thermodynamic limitation for Ca 2ϩ handling contributes to decreased contractile reserve in rat hearts. Am.—The free energy release from ATP hydrolysis (0⌬G ϳp 0) is decreased by inhibiting the creatine kinase (CK) reaction, which may limit the thermodynamic driving force for the sarcoplasmic reticulum (SR) Ca 2ϩ pumps and thereby cause a decrease in(More)
This paper describes the SOPA-N system used by the LIPN-IIMAS team in Semeval 2016 Semantic Textual Similarity (Task 1). We based our work on the SOPA 2015 system. The SOPA-2015 system used 16 similarity features (including Wordnet, Information Retrieval and Syntactic Dependencies) within a Random Forest learning model. We expanded this system with an Align(More)
Ca 2ϩ regulates the kinet-ics of tension development in intact cardiac muscle. Am. The goal of this study was to determine whether Ca 2ϩ plays a role in regulating tension development kinetics in intact cardiac muscle. In cardiac muscle, this fundamental issue of Ca 2ϩ regulation has been controversial. The approach was to induce steady-state tetanic(More)
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