Albert Manuel Orozco Camacho

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The extracellular concentration of glutamate is highly regulated by transporter proteins, due to its neurotoxic properties. Dysfunction or reverse activation of these transporters is related to the extracellular accumulation of excitatory amino acids and neuronal damage associated with ischemia and hypoglycemia. We have investigated by microdialysis the(More)
The concentration of glutamate is regulated to ensure neurotransmission with a high temporal and local resolution. It is removed from the extracellular medium by high-affinity transporters, dependent on the maintenance of the Na(+) gradient through the activity of Na(+),K(+)-ATPases. Failure of glutamate clearance can lead to neuronal damage, named(More)
Neuronal death associated with cerebral ischemia and hypoglycemia is related to increased release of excitatory amino acids (EAA) and energy failure. The intrahippocampal administration of the glycolysis inhibitor, iodoacetate (IOA), induces the accumulation of EAA and neuronal death. We have investigated by microdialysis the role of exocytosis, glutamate(More)
Normal zinc levels are essential for the development and maintenance of immune functions; Zn deficiency is detrimental to the embryo and offspring of experimental animals, especially concerning immune development. It is known that Zn supplementation improves immune responses. To further explore the relation between Zn administration and the metal in vitro(More)
Chronic alcohol-induced changes in cardiac contractility are not due to changes in the cytosolic Ca 2ϩ transient. Am.—Long-standing heavy alcohol consumption acts as a chronic stress on the heart. It is thought that alcohol-induced changes of contractility are due to altered Ca 2ϩ handling, but no measurements of cytosolic Ca 2ϩ ([Ca 2ϩ ] c) after chronic(More)
Chronic dipyridamole therapy produces sustained protection against cardiac ische-mia-reperfusion injury. Am.—Sustained protection against ischemia-reperfusion injury is not available for patients at risk for myocardial infarction who may require emergent reperfusion therapy. Whereas ischemic precondition-ing and adenosinergic agents reduce myocardial(More)
This paper describes the SOPA-N system used by the LIPN-IIMAS team in Semeval 2016 Semantic Textual Similarity (Task 1). We based our work on the SOPA 2015 system. The SOPA-2015 system used 16 similarity features (including Wordnet, Information Retrieval and Syntactic Dependencies) within a Random Forest learning model. We expanded this system with an Align(More)
Ca 2ϩ regulates the kinet-ics of tension development in intact cardiac muscle. Am. The goal of this study was to determine whether Ca 2ϩ plays a role in regulating tension development kinetics in intact cardiac muscle. In cardiac muscle, this fundamental issue of Ca 2ϩ regulation has been controversial. The approach was to induce steady-state tetanic(More)
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