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Respiratory syncytial virus (RSV) infection in the neonate can alter respiratory rates, i.e., lead to episodes of apnea. We show that RSV G glycoprotein reduces respiratory rates associated with the induction of substance P (SP) and G glycoprotein-CX3CR1 interaction, an effect that is inhibited by treatment with anti-G glycoprotein, anti-SP, or anti-CX3CR1… (More)
Data are presented for diagnoses of HIV infection reported to CDC through December 2012. The HIV Surveillance Supplemental Report is not copyrighted and may be used and copied without permission. Citation of the source is, however, appreciated. Suggested citation Centers for Disease Control and Prevention. Monitoring selected national HIV prevention and… (More)
The kinetics and magnitude of SP receptor expression was determined for bronchoalveolar leukocyte cell subsets from BALB/c mice in the primary immune response to respiratory syncytial virus (RSV) and human parainfluenza virus-3 (PIV3) infection, and in the secondary immune response to RSV and PIV3 challenge. In both the primary and secondary responses to… (More)
BACKGROUND In 2006, a mumps outbreak occurred on a university campus despite ≥ 95% coverage of students with 2 doses of measles-mumps-rubella (MMR) vaccine. Using plasma samples from a blood drive held on campus before identification of mumps cases, we compared vaccine-induced preoutbreak mumps antibody levels between individuals who developed mumps (case… (More)
Disease Description Mumps is an acute viral illness caused by a paramyxovirus. The classic symptom is parotitis, a swelling of one or more of the salivary glands. 1 Nonspecific symptoms, including myalgia, anorexia, malaise, headache, and low-grade fever, may precede parotitis by several days. As many as 20–40% of infections are asymptomatic and nearly 50%… (More)
We report a case of congenital rubella syndrome in a child born to a vaccinated New Jersey woman who had not traveled internationally. Although rubella and congenital rubella syndrome have been eliminated from the United States, clinicians should remain vigilant and immediately notify public health authorities when either is suspected.
Persons who died of Ebola virus disease at home in rural communities in Liberia and Guinea resulted in more secondary infections than persons admitted to Ebola treatment units. Intensified monitoring of contacts of persons who died of this disease in the community is an evidence-based approach to reduce virus transmission in rural communities.
Measles is an acute viral illness caused by a virus in the family paramyxovirus, genus Morbillivirus. Measles is characterized by a prodrome of fever (as high as 105°F) and malaise, cough, coryza, and conjunctivitis, followed by a maculopapular rash. 1 The rash usually appears 14 days after exposure and spreads from head to trunk to lower extremities.… (More)