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- Panos Z Anastasiadis, Sun Young Moon, +4 authors Albert B. Reynolds
- Nature Cell Biology
- 2000
RhoA organizes actin stress fibres and is necessary for cell transformation by oncogenes such as src and ras. Moreover, RhoA is implicated in cadherin clustering during the formation of adherens… (More)
- Michael D Schaller, Cheryl A. Borgman, Bradley S Cobb, R R Vines, Albert B. Reynolds, John T. Parsons
- Proceedings of the National Academy of Sciences…
- 1992
Expression of the Rous sarcoma virus-encoded oncoprotein, pp60v-src, subverts the normal regulation of cell growth, which results in oncogenic transformation. This process requires the intrinsic… (More)
The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor.
- Juliet M. Daniel, Albert B. Reynolds
- Molecular and cellular biology
- 1999
p120(ctn) is an Armadillo repeat domain protein with structural similarity to the cell adhesion cofactors beta-catenin and plakoglobin. All three proteins interact directly with the cytoplasmic… (More)
- Michael A. Davis, Renee C Ireton, Albert B. Reynolds
- The Journal of cell biology
- 2003
p120-catenin stabilizes epithelial cadherin (E-cadherin) in SW48 cells, but the mechanism has not been established. Here, we show that p120 acts at the cell surface to control cadherin turnover,… (More)
- Molly A. Thoreson, Panos Z Anastasiadis, +5 authors Albert B. Reynolds
- The Journal of cell biology
- 2000
p120(ctn) is a catenin whose direct binding to the juxtamembrane domain of classical cadherins suggests a role in regulating cell-cell adhesion. The juxtamembrane domain has been implicated in a… (More)
- Hua Wu, Albert B. Reynolds, Steven B. Kanner, R R Vines, John T. Parsons
- Molecular and cellular biology
- 1991
Transformation of cells by the src oncogene results in elevated tyrosine phosphorylation of two related proteins, p80 and p85 (p80/85). Immunostaining with specific monoclonal antibodies revealed a… (More)
- Gregg A. Wildenberg, Michael Robert Dohn, +4 authors Albert B. Reynolds
- Cell
- 2006
Integration of receptor tyrosine kinase, integrin, and cadherin activities is crucial for normal cell growth, motility, and adhesion. Here, we describe roles for p120-catenin (p120) and p190RhoGAP… (More)
- Panos Z Anastasiadis, Albert B. Reynolds
- Current opinion in cell biology
- 2001
Three recent reports indicate that p120-catenin can modulate the activities of RhoA, Rac and Cdc42, suggesting an elegant and previously unexpected mechanism for regulating the balance between… (More)
- Michael A. Davis, Albert B. Reynolds
- Developmental cell
- 2006
p120 catenin is thought to be a key regulator of E-cadherin function and stability, but its role(s) in vivo is poorly understood. To examine these directly, we generated a conditional p120 knockout… (More)
Although p120-catenin regulates adherens junction (AJ) stability in cultured cells, genetic studies in lower eukaryotes have not revealed a role for this protein in vivo. Using conditional targeting… (More)