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Microbial secondary metabolites are low molecular mass products, not essential for growth of the producing cultures, but very important for human health. They include antibiotics, antitumor agents, cholesterol-lowering drugs, and others. They have unusual structures and are usually formed during the late growth phase of the producing microorganisms. Its… (More)
Antibiotics are low-molecular-mass products of secondary metabolism, nonessential for the growth of producing organisms, but very important for human health. They have unusual structures and are most often formed during the late growth phase of the producing microorganisms. Their production arises from intracellular intermediates, which are condensed into… (More)
In Streptomyces, carbon utilization is of significant importance for the expression of genes involved in morphological differentiation and antibiotic production. Glucose is mainly transported by GlcP, a membrane protein encoded by glcp. In Streptomyces coelicolor, this protein is encoded by sco5578. However, there is little information about the physiology… (More)
1. New ways to combat pathogenic bacteria – bacteriophage lytic enzymes as an alternative to antibiotic therapy 2. From sewage-treatment plants to phage therapy: step-by-step phage analysis and application Piotr Golec 3. Staphylococcal Twort-like phages encode a homolog of bacterial virulence determinants. Can we use these phages for therapeutic purposes?