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Metaverses are immersive three-dimensional virtual worlds in which people interact as avatars with each other and with software agents, using the metaphor of the real world but without its physical limitations. The ubiquitous availability of high speed Internet access has spurred enormous interest in virtual worlds like Second Life and World of Warcraft,(More)
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BACKGROUND Testicular germ cell tumour (TGCT) is the most common malignant tumour in young males. Although aberrant DNA methylation is implicated in the pathophysiology of many cancers, only a limited number of genes are known to be epigenetically changed in TGCT. This report documents the genome-wide analysis of differential methylation in an in vitro(More)
Virtual worlds such as Linden Lab's Second Life are pervading our everyday world and already impacting organizational practices involving virtual teams and virtual-world project management. C onsider a world in which you can conduct training sessions and bring together experts from around the globe in a single, common environment; hold effective meetings in(More)
Murine gammaherpesvirus 68 (MHV-68) is a virus of wild rodents and is a convenient small animal model for studies of gammaherpesvirus pathogenesis. We have sequenced 6162 bp at the left end of the MHV-68 genome and identified two unique open reading frames (ORFs) (ORF2 and ORF3) and an ORF (ORF1) which displays similarity to poxvirus members of the serpin(More)
In the testicular cancer cell line, NT2, we previously demonstrated that differentially methylated regions were located in introns or intergenic regions, and postulated these might regulate non-coding RNAs. Three microRNAs and three small nucleolar RNAs were differentially methylated; one, miR-199a, was associated with the progression and prognosis of(More)
The disparities in access to and use of information and communication technologies (ICTs) comprise a divide between those who can and cannot reap the benefits of the information superhighway. Electronic commerce appears to enable this divide to be overcome. This paper provides insight into the ways in which development is brought about through ICTs.(More)
The ability to exchange opinions and experiences online is known as online word of mouth (WOM). Due to the high acceptance of consumers and their apparent reliance on online WOM it is important for organizations to understand how it works and what kind of impact it has on product sales. Using the well established notions of volume and valence to describe(More)