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  • Alan Salamy
  • Journal of clinical neurophysiology : official…
  • 1984
The various parameters of the auditory brainstem response (ABR) undergo distinct maturational transformations in early life. The multiplicity of observed changes suggests unique timetables for development of the contributing neural elements. Although the precise physioanatomic substrate of the ABR remains speculative, experimental manipulations and(More)
Since maturation of ABR amplitude and latency in principle are dependent on innate as well as environmental factors and the health of the infant, it is conceivable that prematurely born infants show a maturation profile that is different from that of full term infants. In order to unequivocally address this we analyzed ABRs recorded in 465 full term infants(More)
Average brainstem potentials evoked by auditory stimuli were recorded from the scalp's surface of human newborns and infants, 6 weeks, 3 months, 6 months and 1 year of age as well as from normal adults. The auditory processes related to peripheral transmission (PT) and central transmission (CT) were shown to mature at differential rates during the first(More)
Bilateral ABRs were recorded from 452 infants 32-45 weeks conceptional age. Differences in laterality, gender and appropriateness for gestational age were investigated in order to increase our understanding of developmental processes in early life. Rate effects were also studied in a subsample of infants (145 ears). All subjects were free of conditions(More)
We have examined the role of serotonergic and/or dopaminergic mechanism in the mediation of the nicotine-induced depression of brainstem auditory evoked responses (BAER) to auditory stimuli. Nicotine produced dose- and time-dependent decreases in BAER amplitude. Administration of serotonin-depleting drugs (reserpine or p-chlorophenylalanine (PCPA),(More)
Auditory brain stem responses were recorded in full term infants (N = 465) and in unselected preterm infants (N = 178) who were tested in, respectively, 10 and 12 age groups from birth until 5 yr. The latencies of waves I and V as well as the wave I-wave V delay and the wave V to wave I amplitude ratio were compared at the various age groups. It was found(More)
Middle component AERs to brief click stimuli were recorded from 60 subjects in four age groups to assess age effects on waveform, latency, and amplitude. Replicable responses similar in waveform to those recorded in adults were observed in 3 - 4-year-old children, full-term newborns, and premature infants tested as early as the 31st postconceptional week.(More)