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In this paper, we investigate the approach of using low cost PC cluster to parallelize the computation of iceberg-cube queries. We concentrate on techniques directed towards online querying of large, high-dimensional datasets where it is assumed that the total cube has net been precomputed. The algorithmic space we explore considers trade-offs between(More)
The insulin-dependent tyrosine kinase activity (TKA) of the insulin receptor (IR) plays an essential role in insulin signaling. Thus, dysregulation of IR-TKA might be an important element in the states of insulin resistance. A phosphorylated rat hepatic glycoprotein (pp63) acting as an inhibitor of IR-TK has been described. In search of the human homolog of(More)
—In this paper, we describe the design, implementation, and modeling of a runtime kernel to support the processor farm paradigm on multicomputers. We present a general topology-independent framework for obtaining performance models to predict the performance of the start-up, steady-state, and wind-down phases of a processor farm. An algorithm is described,(More)
S100a is a heterodimeric, acidic calcium-binding protein that interacts with calmodulin antagonists in a Ca2(+)-dependent manner. In order to study the behavior of the hydrophobic domain on S100a when bound to Ca2+, its interaction with trifluoperazine (TFP) was investigated using 16F nuclear magnetic resonance (NMR) and circular dichroism (CD)(More)
UNLABELLED Strontium ions were discovered to exert a dual effect on bone turnover, namely an inhibition of cell-driven bone resorption and a simultaneous stimulation of new bone tissue formation. A variety of strontium containing calcium phosphate bone cements (SrCPC) have been developed to benefit from both effects to locally support the healing of(More)