Alan Purvis

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Computer Interfaces, neuroprothesis devices and modeling and simulation of neural networks have led to increased research activity in algorithms for the detection, isolation and classification of Action Potentials (AP) from noisy data trains. Current techniques in the field of 'unsupervised no-prior knowledge' biosignal processing include energy operators,(More)
At the 1990 ICMC, this research group presented a paper on a multi-transputer based system [Bailey et al., 1990] and demonstrated a prototype module consisting of 16 transputers on a single card. During the intervening period, ten of these cards have been developed into an operational audio processing network, using 160 x T800 floating-point transputers,(More)
The polymerization of laminins into a cell-associated network is a key process in basement membrane assembly. Network formation is mediated by the homologous short arm tips of the laminin heterotrimer, each consisting of a globular laminin N-terminal (LN) domain followed by a tandem of laminin-type epidermal growth factor-like (LEa) domains. How the short(More)
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. This license does not permit commercial exploitation or the creation of derivative works without specific permission. The(More)
This paper presents a combined fault detection and discrimination strategy for CMOS logic incorporating active resource mitigation and monitoring. The approach is demonstrated for a NOR gate using a dual redundant gate design with selective mitigation and analogue or digital detection. The potential benefits of the approach are discussed with respect to(More)
Under physiological conditions, the pentameric human plasma protein serum amyloid P component (SAP) binds hexanoyl bis(D-proline) (R-1-{6-[R-2-carboxy-pyrrolidin-1-yl]-6-oxo-hexanoyl}pyrrolidine-2-carboxylic acid; CPHPC) through its D-proline head groups in a calcium-dependent interaction. Cooperative effects in binding lead to a substantial enhancement of(More)