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CONTEXT Recent research suggests that variation in the gene encoding dystrobrevin binding protein (DTNBP1) confers susceptibility to schizophrenia. Thus far, no specific risk haplotype has been identified in more than 1 study. OBJECTIVES To confirm DTNBP1 as a schizophrenia susceptibility gene, to identify and replicate specific risk and protective(More)
Recently, it has been reported that genetic variants around the gene neuregulin 1 are associated with schizophrenia in an Icelandic sample. Of particular interest was the presence of a single-risk haplotype that was significantly over-represented in schizophrenic individuals compared to controls (15.4 : 7.5%, P=6.7 x 10(-6)). We have attempted to replicate(More)
Introduction In this paper we present for the first time clinical results of breast cancer detection using a radar-based UWB microwave system developed at the University of Bristol. Additionally, the system overview and some experimental laboratory results are presented as well. For the clinical result shown in this contribution, we compare images obtained(More)
—We consider the problem of sensor-mission assignment as that of allocating a collection of intelligence, surveillance and reconnaisance (ISR) assets (including sensors and sensor platforms) to a set of mission tasks in an attempt to satisfy the ISR requirements of those tasks. This problem is exacerbated in a coalition context because the full range of(More)
The KRAFT (Knowledge Reuse And Fusion/Transformation) system [1] is a research prototype which is being developed collaboratively with BT by three UK universities-Aberdeen, Cardiff and Liverpool-for combining and transforming constraint based knowledge. The KRAFT system is designed to help its users to: locate relevant data and constraint knowledge held in(More)
In the e-Science context, workflow technologies provide a problem-solving environment for researchers by facilitating the creation and execution of experiments from a pool of available data and computation services. Recent activities in the field of social simulation indicate the need to improve the scientific rigour of agent-based modelling by making(More)
Using similar techniques to Ground Penetrating Radars, microwave detection of breast tumours is a potential non-ionising and non-invasive alternative to traditional body-imaging techniques. In order to develop an imaging system, the team at Bristol have been working on a number of antenna array prototypes, based around a stacked-patch element-starting with(More)
—In this paper, we show how knowledge representation and reasoning techniques can support sensor-mission assignment , proceeding from a high-level specification of information requirements, to the allocation of assets such as sensors and platforms. In our previous work, we showed how assets can be matched to mission tasks by formalising the military(More)