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Recent innovations in biomedicine seem poised to revolutionize medical practice. At the same time, disease and disability are increasing among younger populations. This paper considers how these confluent trends will affect the elderly's health status and health care spending over the next thirty years. Because healthier people live longer, cumulative(More)
In order to make more informed healthcare decisions, consumers need information systems that deliver accurate and reliable information about their illnesses and potential treatments. Reports of randomized clinical trials (RCTs) provide reliable medical evidence about the efficacy of treatments. Current methods to access, search for, and retrieve RCTs are(More)
BACKGROUND The appropriate roles for several diagnostic tests for coronary disease are uncertain. OBJECTIVE To evaluate the cost-effectiveness of alternative approaches to diagnosis of coronary disease. DESIGN Meta-analysis of the accuracy of alternative diagnostic tests plus decision analysis to assess the health outcomes and costs of alternative(More)
We construct and implement a test of rational consumer behavior in a high-stakes financial market. We apply our test to secondary life insurance markets, where consumers with a life-threatening illness sell their life insurance policies to firms in return for an up-front payment. This secondary life insurance market has been largely ignored by economists,(More)
Stanford's two decades of success in linking medical informatics and health services research in both training and investigational activities reflects advantageous geography and history as well as natural synergies in the two areas. Health services research and medical informatics at Stanford have long shared a quantitative, analytic orientation, along with(More)
Concept specific lexicons (e.g. diseases, drugs, anatomy) are a critical source of background knowledge for many medical language-processing systems. However, the rapid pace of biomedical research and the lack of constraints on usage ensure that such dictionaries are incomplete. Focusing on disease terminology, we have developed an automated, unsupervised,(More)
BACKGROUND The optimal community-level approach to control pandemic influenza is unknown. METHODS We estimated the health outcomes and costs of combinations of 4 social distancing strategies and 2 antiviral medication strategies to mitigate an influenza pandemic for a demographically typical US community. We used a social network, agent-based model to(More)
This paper estimates the value of medical research, using cardiovascular disease as a case study. We highlight two roles of medical research: the new therapies it leads to; the information that is provided to consumers, allowing for health-improving behavioral changes. We estimate the return to new medical treatments at about 4 to 1 and the return to health(More)