Alan L Elliott

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OBJECTIVE To evaluate diurnal variation of biomarkers in subjects with osteoarthritis (OA) of the knee. METHODS Twenty subjects with radiographic knee OA were admitted to the General Clinical Research Center of Duke University for an overnight stay to undergo serial blood and urine sampling. Biomarkers measured included serum hyaluronan (HA), cartilage(More)
OBJECTIVE Serum hyaluronan (HA) has been proposed as a potential biomarker of osteoarthritis (OA). We examined associations between serum HA and radiographic OA in an ethnically diverse, population-based sample. METHODS Participants were selected from the Johnston County Osteoarthritis Project, using stratified simple random sampling to achieve balance(More)
PURPOSE Serum hyaluronan (HA) was evaluated for diurnal variation in participants with osteoarthritis (OA) of the knee. METHODS Twenty participants with radiographic OA of at least one knee were admitted overnight to the General Clinical Research Center for serial serum sampling. Serum was obtained between 6:00 p.m. and 8:00 p.m. on Day 1 (T3) after a day(More)
1. Observations were made upon five subjects who flew through 4(1/2)-6 time zones, four of them returning later to their starting point, and upon twenty-three subjects experiencing simulated 6 or 8 hr time zones shifts in either direction in an isolation unit.2. Measurements were made of plasma concentration of 11-hydroxycorticosteroids, of body(More)
Conroy, R. T. W. L., Elliott, A. L., and Mills, J. N. (1970). Brit. J. industr. Med., 27, 356-363. Circadian excretory rhythms in night workers. Urine samples have been collected from day and night shift workers in a light engineering factory over periods of 24 or 48 hours during which blood was also collected for determination of plasma(More)
OBJECTIVE To assess associations between joint-specific hand symptoms and self-reported and performance-based functional status. METHODS Participants were from the population-based Johnston County Osteoarthritis Project. Symptoms in the distal interphalangeal (DIP), proximal interphalangeal (PIP), first carpometacarpal (CMC), and metacarpophalangeal (MCP)(More)