Alan Jennings

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Simultaneous iteration methods are extensions of the power method whereby iteration is carried out with a number of trial vectors tha t converge onto the eigenvectors corresponding to the dominant eigenvalues. T h e y are particularly suitable where the matrix requiring eigensolution is large and sparse, or where approximations to the required dominant(More)
A 30-year-old manufacturing process for the biologic product L-asparaginase from the plant pathogen Erwinia chrysanthemi was rigorously qualified and validated, with a high level of agreement between validation data and the 6-year process database. L-Asparaginase exists in its native state as a tetrameric protein and is used as a chemotherapeutic agent in(More)
Received 12 December 1977, 12 June 1979, and 14 April 1980. Permmsion to copy without fee all or part of thin material is granted provided that the copras are not made or distributed for direct commercial advantage, the ACM copymght notice and the title of the publication and its date appear, and notice is gwen that copying is by permission of the(More)
Noncontact measurements of flexible and moving structures have the challenge of obtaining high speed, accurate and registered data over a long range. Many noncontact measurement methods are based on the object staying aligned with the sensor. Yet sometimes the desired loading is a result of the motion interacting with structural dynamics as is the case with(More)
In order to generate further characterisation data for the lyophilised product Erwinia chrysanthemi l-asparaginase, reconstituted drug product (DP; marketed as Erwinase or Erwinaze) was analysed for subvisible (2–10 μm) particulate content using both the light obscuration (LO) method and the newer flow-imaging microscopy (FIM) technique. No correlation of(More)
Noncontact dynamic measurements of lightweight flexible aerospace structures in motion present several challenges. Achieving high frequency and high resolution measurements requires multiple registered metrology systems. Many noncontact measurement methods are based on the object staying aligned with the sensor. Yet sometimes the desired loading is a result(More)
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