Alan J. Parkinson

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Transposable element ISHp608 of Helicobacter pylori: nonrandom geographic distribution, functional organization, and insertion specificity.

Dangeruta Kersulyte, Billie Velapatiño, +6 authors Douglas E. Berg
Journal of bacteriology
2002

A new member of the IS605 transposable element family, designated ISHp608, was found by subtractive hybridization in Helicobacter pylori. Like the three other insertion sequences (ISs) known in this… (More)

Sequential inactivation of rdxA (HP0954) and frxA (HP0642) nitroreductase genes causes moderate and high-level metronidazole resistance in Helicobacter pylori.

Jin Yong Jeong, Asish Kumar Mukhopadhyay, +20 authors Douglas E. Berg
Journal of bacteriology
2000

Helicobacter pylori is a human-pathogenic bacterial species that is subdivided geographically, with different genotypes predominating in different parts of the world. Here we test and extend an… (More)

Invasive pneumococcal disease caused by nonvaccine serotypes among alaska native children with high levels of 7-valent pneumococcal conjugate vaccine coverage.

Rosalyn J. Singleton, Thomas W. Hennessy, +6 authors Alan J. Parkinson
JAMA
2007

CONTEXT With routine childhood vaccination using heptavalent pneumococcal conjugate vaccine, one concern has been the potential for emergence and expansion of replacement disease caused by serotypes… (More)

The relationship among previous antimicrobial use, antimicrobial resistance, and treatment outcomes for Helicobacter pylori infections.

Brian J. McMahon, Thomas W. Hennessy, +8 authors J. Corey Butler
Annals of internal medicine
2003

Context Adverse effects of previous antibiotic use in patients with Helicobacter pylori infections are unclear. Contribution This retrospective study examined relationships between resistant H.… (More)

The Alaska Haemophilus influenzae Type b Experience: Lessons in Controlling a Vaccine-Preventable Disease

Rosalyn J. Singleton, Laura L. Hammitt, +6 authors J. Corey Butler
Pediatrics
2006

OBJECTIVE Before 1991, Alaska Native children experienced one of the highest rates of invasive Haemophilus influenzae type b disease. H influenzae type b vaccine has led to a near-elimination of… (More)

Experience with the prevention of invasive Haemophilus influenzae type b disease by vaccination in Alaska: the impact of persistent oropharyngeal carriage.

Rosalyn J. Singleton, Lisa R. Bulkow, Orin S Levine, J. Corey Butler, Thomas W. Hennessy, Alan J. Parkinson
The Journal of pediatrics
2000

OBJECTIVES To report the epidemiology of invasive Haemophilus influenzae type b (Hib) disease in high-risk Alaska Native infants before and after universal infant Hib vaccination and evaluate an… (More)

Evaluation of polymerase chain reaction for diagnosis of pneumococcal pneumonia.

Karen M. Rudolph, Alan J. Parkinson, C. Black, Leonard W. Mayer
Journal of clinical microbiology
1993

To test the ability of the polymerase chain reaction (PCR) to detect Streptococcus pneumoniae in blood, we generated two sets of nested primers. The first defined 559-bp and 649-bp regions of the… (More)

Elimination of hepatocellular carcinoma and acute hepatitis B in children 25 years after a hepatitis B newborn and catch-up immunization program.

Brian J. McMahon, Lisa R. Bulkow, +4 authors Alan J. Parkinson
Hepatology
2011

UNLABELLED Alaska Native people experience the highest rates of acute and chronic hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) in the United States. We examined the effect of… (More)

Epidemiology of Haemophilus influenzae Serotype a, North American Arctic, 2000–2005

Michael G. Bruce, Shelley L. Deeks, +12 authors Alan J. Parkinson
Emerging infectious diseases
2008

Before the introduction of Haemophilus influenzae type b (Hib) conjugate vaccines, rates of invasive H. influenzae disease among indigenous people of the North American Arctic were among the highest… (More)

International Circumpolar Surveillance, An Arctic Network for the Surveillance of Infectious Diseases

Alan J. Parkinson, Michael G. Bruce, Tammy Zulz
Emerging infectious diseases
2008

Peoples of the Arctic and sub-Arctic regions live in social and physical environments that differ substantially from those of their more southern-dwelling counterparts. The cold northern climate… (More)

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