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Phenotypic stereotypes are traits, often polygenic, that have been stringently selected to conform to specific criteria. In dogs, Canis familiaris, stereotypes result from breed standards set for conformation, performance (behaviors), etc. As a consequence, phenotypic values measured on a few individuals are representative of the breed stereotype. We used(More)
Traits that have been stringently selected to conform to specific criteria in a closed population are phenotypic stereotypes. In dogs, Canis familiaris, such stereotypes have been produced by breeding for conformation, performance (behaviors), etc. We measured phenotypes on a representative sample to establish breed stereotypes. DNA samples from 147 dog(More)
Detailed examination of the water column, sediments, and interstitial waters was conducted in Balmer Lake, Ontario, Canada, in 1993-1994 and 1999 in order to assess the seasonal and interannual controls governing the behavior of As. High-resolution profiles of dissolved (<0.45 microm) Fe, Mn, SO4(2-), and sigmaH2S across the sediment-water interface(More)
The relationship between lake trophic status, sedimentary redox conditions and As mobility was examined in mine-impacted Balmer Lake, Canada. Under the current redox regime, the reductive dissolution of As-bearing Fe(III) oxyhydroxides occurs in close proximity to the sediment-water interface, resulting in the remobilization of dissolved As in the shallow(More)
A combination of Cu speciation analysis and toxicity testwork was conducted to assess the behavior, speciation, and bioavailability of Cu in a stream system rich in dissolved organic carbon (DOC) downstream of a mine-impacted lake (East Lake, ON, Canada). Elevated levels (approximately 50 microg/L) of Cu exist in the lake due to the release of dissolved Cu(More)
The biogeochemical mechanisms of Se exchange between water and sediments in two contrasting lentic environments were assessed through examination of Se speciation in the water column, porewater, and sediment. High-resolution (7 mm) vertical profiles of <0.45 μm Se species across the sediment-water interface demonstrate that the behavior of dissolved Se(VI),(More)
The post-depositional behavior of Cu in a gold-mining polishing pond (East Lake, Canada) was assessed after mine closure by examination of porewater chemistry and mineralogy. The near-surface (upper 1.5 cm) sediments are enriched in Cu, with values ranging from 0.4 to 2 wt %. Mineralogical examination revealed that the bulk of the Cu inventory is present as(More)
Dear Sir, We read with interest the study by Berthold et al. [1], detailing the effect of atorvastatin on the markers of bone turnover in a small, randomized placebo-controlled study of 51 postmenopausal women. There are a number of points that have not been addressed in the discussion. Since none of the participants had DEXA performed, we cannot assume(More)
Metabotropic glutamate receptors (mGluRs) constitute an important family of the G-protein coupled receptors. Due to their widespread distribution in the central nervous system (CNS), these receptors are attractive candidates for understanding the molecular basis of various cognitive processes as well as for designing inhibitors for relevant psychiatric and(More)
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