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A prospective randomized phase III trial was carried out at Songklanagarind Hospital from August 1988 to December 1990. The objectives of the study were to evaluate the effect of chemotherapy regimen in squamous cell carcinoma of the esophagus and to determine whether induction chemotherapy improves symptom-free period and survival in these patients(More)
A prospective study was conducted following 1364 major operations at the 450-bed Hungvuong Obstetric and Gynaecological Hospital in HoChiMinh City, Vietnam, from 1 May to 30 September 1997 to characterize postoperative hospital-acquired infections. These infections were identified by ward rounds, review of laboratory results and patient follow-up until 30(More)
Videofluorography (VFG) and manometry were used to evaluate 111 patients who were diagnosed with globus hystericus. Most of the globus patients were affected by functional diseases and the underlying pathology could be revealed by VFG in 73.9 per cent of the series and by manometry in 80.2 per cent. There were 10.8 per cent of the series in which VFG and(More)
Heavy maternal workloads are considered to be hazardous to the fetus. The effects of physical activity during pregnancy on low birth weight (LBW), small for gestational age (SGA), and prematurity were assessed from a sample of 1797 women in a follow-up study at the antenatal clinic of two hospitals in southern Thailand. The women were interviewed twice, at(More)
AIM To observe the efficiency and safety of thymosin-alpha1 treatment in patients with hepatitis B e antigen (HBeAg) and HBV DNA positive chronic hepatitis. METHODS Sixty-two patients were randomly divided into groups A and B. The patients in group A received subcutaneous injection of 1.6 mg thymosin-alpha1, twice a week (T-alpha1 group) for six months,(More)
OBJECTIVE To determine the outcome of severe dengue viral infection (DVI) and the main dengue fatality risk factors. STUDY DESIGN The medical records of patients aged <15 years admitted to Songklanagarind Hospital in southern Thailand during 1989-2011 were reviewed. Patients who had dengue hemorrhagic fever (DHF) grades III-IV, organ failure(More)
OBJECTIVE To determine postcesarean complications and identify independent risk factors for surgical site infection. METHODS We studied a cohort of 969 women delivered by cesarean between May and August 1997. Infections were determined by examinations during ward rounds, reviews of laboratory results, and follow-up for 30 days after discharge. Risk(More)
OBJECTIVE/HYPOTHESIS The objectives were to test the hypothesis that synchronous contraction of the thyrohyoid muscle by electrical stimulation during swallowing would improve dysphagia resulting from reduced laryngeal elevation and to evaluate the effectiveness of the synchronous electrical stimulator. STUDY DESIGN Prospective study. METHODS Eleven(More)
BACKGROUND AND PURPOSE The most common prescribed antiepileptic drugs (AEDs), phenytoin and valproate, are potent enzyme inducers and inhibitors of the cytochrome P450 system, which interfere with lipid profile and glucose homeostasis. Studies on this topic have suffered from inadequate assessment of confounders and have rarely included glucose homeostasis(More)
SETTING One hundred and twenty-nine counties in Yunnan, a mountainous province in China. OBJECTIVE To document the relationship between patient delays and distance to local county tuberculosis (TB) centres. DESIGN A computerised medical record-based study of a cohort of 10356 new smear-positive TB cases in 2005. RESULTS The median total delay was 71(More)