Alan Fine

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Biologically inspired neural networks which perform temporal sequence learning and generation are frequently based on hetero-associative memories. Recent work by Jensen and Lisman has suggested that a model which connects an auto-associator module to a hetero-associator module can perform this function. We modify this architecture in a simplified model(More)
Temporal sequence generation readily occurs in nature. For example performing a series of motor movements or recalling a sequence of episodic memories. Proposed networks which perform temporal sequence generation are often in the form of a modification to an auto-associative memory by using hetero-associative or time-varying synaptic strengths, requiring(More)
The decision to initiate invasive, first-inhuman trials involving Parkinson's disease presents a vexing ethical challenge. Such studies present significant surgical risks, and high degrees of uncertainty about intervention risks and biological effects. We argue that maintaining a favorable risk-benefit balance in such circumstances requires a higher than(More)
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