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ÐA framework for automatic landmark indentification is presented based on an algorithm for corresponding the boundaries of two shapes. The auto-landmarking framework employs a binary tree of corresponded pairs of shapes to generate landmarks automatically on each of a set of example shapes. The landmarks are used to train statistical shape models known as(More)
MRI is a valuable imaging modality for assessment of the articular cartilage in rheumatoid arthritis (RA) and is potentially of use in monitoring disease progression and response to therapy. In this study, we investigated the sources of error in volume measurements obtained by segmentation of MR images of knee cartilage in patients with RA and followed(More)
For patients undergoing screening computed tomography colonography (CTC), an opportunity exists for bone mineral density (BMD) screening without additional radiation exposure using quantitative computed tomography (QCT). This study investigated the use of dual-energy X-ray absorptiometry (DXA)-equivalent QCT Computed Tomography X-Ray Absorptiometry (CTXA)(More)
Bone mineral density (BMD) estimates for the proximal femur using Dual Energy X-ray Absorptiometry (DXA) are currently considered the standard for making a diagnosis of osteoporosis in an individual patient using BMD alone. We have compared BMD results from a commercial Quantitative CT (QCT) BMD analysis system, "CTXA Hip", which provides clinical data for(More)
A previous publication has described a method of pairwise 3D surface correspondence for the automated generation of landmarks on a set of examples from a class of shape [3]. In this paper we describe a set of improved algorithms which give more accurate and more robust results. We show how the pairwise corresponder can be used in a extension of an existing(More)
OBJECTIVE For patients undergoing contrast-enhanced CT examinations that include the proximal femur, an opportunity exists for concurrent screening bone mineral density (BMD) measurement. We investigated the effect of IV contrast enhancement on CT-derived x-ray absorptiometry areal BMD measurement. MATERIALS AND METHODS Our cohort included 410 adults(More)
For patients undergoing routine contrast-enhanced CT examinations, an opportunity exists for concurrent osteoporosis screening without additional radiation exposure or patient time using proximal femur CT X-ray absorptiometry (CTXA). We investigated the effect of i.v. contrast enhancement on femoral neck CTXA T-score measurement compared with DXA. This(More)
A method for corresponding the boundaries of two shapes is presented. The algorithm locates a matching pair of sparse polygonal approximations, one for each of a pair of boundaries, by minimising a cost function using a greedy algorithm. The cost function expresses the dissimilarity in both the shape and representation error (with respect to the deening(More)