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The laboratory mouse is the premier model system for studies of mammalian development due to the powerful classical genetic analysis possible (see also the Jackson Laboratory web site, http://www.jax.org/) and the ever-expanding collection of molecular tools. To enhance the utility of the mouse system, we initiated a program to generate a large database of(More)
Mobile sensing and mapping applications are becoming more prevalent because sensing hardware is becoming more portable and more affordable. However, most of the hardware uses small numbers of fixed sensors that report and share multiple sets of environmental data which raises privacy concerns. Instead, these systems can be decentralized and managed by(More)
In order to bring about innovation within a community-based context, different stakeholder communities often need to be engaged so that they may appropriately take part in the design process. The 'invisible' work of engagement is frequently overlooked, and yet it plays an important, often pivotal role within many design-based research projects. It revolves(More)
BACKGROUND AND AIMS Autoimmune pancreatitis (AIP) is a poorly understood human disease affecting the exocrine pancreas. The goal of the present study was to elucidate the pathogenic mechanisms underlying pancreatic autoimmunity in a murine disease model. METHODS A transgenic mouse with an S100A4/fibroblast-specific protein 1 (FSP1) Cre-mediated(More)
This paper charts the distinctive challenges of designing mobile experiences for cyclists and presents two studies of mobile cycle-based experiences: one a heritage tour; the other an exploration of a city at dusk involving recording and listening to personal stories. To understand the cyclists' experiences questionnaires, interviews and observations are(More)
We are starting to see a paradigm shift within the field of HCI. We are witnessing researchers leaving the safety and security of their controlled, lab-based environments and moving their research out into 'the wild'. Their studies are carrying out in-situ development and extended engagement, sampling experiences and working with communities in their homes(More)
Doing research 'in the wild is becoming an increasingly popular approach towards developing innovative computing systems and applications. This paper reflects upon a research project conducted in the wild, and key aspects of the work involved in making the project work, to examine current tropes about the approach. It suggests that doing research in the(More)