Alan C. Young

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Acute exacerbations of cystic fibrosis (CF) can be associated with dehydration, hyponatraemia and hypochloraemia. The syndrome of inappropriate anti-diuretic hormone secretion (SIADH) has also been described in CF patients in the setting of hyponatraemia, but may be under-recognised. Diagnosing SIADH has therapeutic implications as it necessitates fluid and(More)
This study aims to describe the pattern of home mechanical ventilation (HMV) usage in Australia and New Zealand. 34 centres providing HMV in the region were identified and asked to complete a questionnaire regarding centre demographics, patient diagnoses, HMV equipment and settings, staffing levels and methods employed to implement and follow-up therapy. 28(More)
BACKGROUND Nocturnal oxyhaemoglobin desaturation is common in cystic fibrosis (CF) but the effect on quality of life (QoL) remains unknown. METHODS Sixty stable CF outpatients with mean age 31±8 years (mean±1 SD), BMI 20.8±3.2 kg/m(2) and FEV(1) 42±13% predicted had arterial blood gas sampling, lung function testing, overnight pulse oximetry and completed(More)
A GaAs low-noise amplifier (LNA) is designed with first-time success using a technique for HEMT modelling which divides the device into intrinsic gate fingers embedded in an analysable metal structure. The gate finger is characterised by de-embedding metallisation from a standard test structure. The device is then re-built, with any geometry or layout that(More)
A 4 × 4 mm QFN overmoulded packaged up-converter has been developed for the 38 GHz point-to-point radio band. The MMIC contains LO-doubler-buffer amplifier, image-reject balanced mixer and RF amplifier with linear gain control and consumes 1.5 watts DC. The up-converter has 7 dB conversion gain, 15 dB image rejection, 15 dB of gain control, 20 dBm(More)
A new technique is proposed for the design of linear power amplifiers at millimeter-wave frequencies where load-pull of large transistor output cells is difficult. The technique transforms the load-pull data on a small, standard foundry transistor layout to a pair of common-gate contours for the intrinsic device; one source–gate and one drain–gate. These(More)
Background On 21st November 2016, Melbourne experienced an epidemic of 'thunderstorm asthma.' Although previously described in the literature, risk factors and natural history remain incompletely understood. Objective Our aim was to follow up those presenting to the 3 Emergency Departments (EDs) in our health service during the epidemic, and assess their(More)
Bilevel non-invasive positive pressure ventilation (NIV) has become an accepted therapy for acute respiratory acidosis (i.e. pH < 7.35, PaCO2 > 45 mm Hg) in exacerbations of COPD. Used in the appropriate COPD patient and setting, NIV reduces the need for endotracheal intubation and improves survival. NIV improves ventilation in COPD by unloading respiratory(More)
RATIONALE Obstructive sleep apnea (OSA) is associated with impaired renal function, but uncertainty exists over whether OSA treatment can influence renal outcomes. OBJECTIVES To determine the effects of continuous positive airway pressure (CPAP) on renal function in subjects with co-existing OSA and cardiovascular disease. METHODS This was a substudy of(More)
Objective The aim of the present study was to audit the current use of medical records to determine completeness and concordance with other sources of medical information.Methods Medical records for 40 patients from each of five Melbourne major metropolitan hospitals were randomly selected (n=200). A quantitative audit was performed for detailed patient(More)
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