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  • Alan Breier, T P Su, +8 authors David Pickar
  • Medicine, Chemistry
  • Proceedings of the National Academy of Sciences…
  • 1997 (First Publication: 18 March 1997)
  • A major line of evidence that supports the hypothesis of dopamine overactivity in schizophrenia is the psychomimetic potential of agents such as amphetamine that stimulate dopamine outflow. A novelExpand
  • Scot E Purdon, BarryD. Jones, +5 authors Gary D. Tollefson
  • Psychology, Medicine
  • Archives of general psychiatry
  • 2000 (First Publication: 1 March 2000)
  • BACKGROUND The purpose of this investigation was to test the efficacy of novel antipsychotic medications in the treatment of cognitive impairment in early phase schizophrenia. METHODS Sixty-fiveExpand
  • J. S. Street, William S. Clark, +9 authors Alan Breier
  • Psychology, Medicine
  • Archives of general psychiatry
  • 2000 (First Publication: 1 October 2000)
  • BACKGROUND Patients with Alzheimer disease (AD) commonly exhibit psychosis and behavioral disturbances that impair patient functioning, create caregiver distress, and lead to institutionalization.Expand
  • Mauricio Tohen, Kadiamada Nanaiah Roy Chengappa, +11 authors Alan Breier
  • Psychology, Medicine
  • Archives of general psychiatry
  • 2002
  • BACKGROUND A 6-week double-blind, randomized, placebo-controlled trial was conducted to determine the efficacy of combined therapy with olanzapine and either valproate or lithium compared withExpand
  • Mauricio F. Tohen, Thomas Gerardus Maria Jacobs, +10 authors Alan Breier
  • Psychology, Medicine
  • Archives of general psychiatry
  • 2000 (First Publication: 1 September 2000)
  • BACKGROUND We compared the efficacy and safety of olanzapine vs placebo for the treatment of acute bipolar mania. METHODS Four-week, randomized, double-blind, parallel study. A total of 115Expand
  • Pádraig Wright, Melissa Birkett, +10 authors Alan Breier
  • Psychology, Medicine
  • The American journal of psychiatry
  • 2001 (First Publication: 1 July 2001)
  • OBJECTIVE The authors evaluated the comparative efficacy and safety of intramuscular olanzapine, intramuscular haloperidol, and intramuscular placebo for the treatment of acute agitation inExpand