Alan Arroyo

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PURPOSE To compare the safety and activity of DN-101, a new high-dose oral formulation of calcitriol designed for cancer therapy, and docetaxel with placebo and docetaxel. PATIENTS AND METHODS Patients with progressive metastatic androgen-independent prostate cancer and adequate organ function received weekly docetaxel 36 mg/m2 intravenously for 3 weeks(More)
The Path Partition Conjecture for digraphs states that for every digraph D, and every choice of positive integers λ 1 , λ 2 such that λ 1 + λ 2 equals the order of a longest directed path in D, there exists a partition of D in two subdigraphs D 1 , D 2 such that the order of the longest path in D i is at most λ i for i = 1, 2. We present sufficient(More)
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